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Mac and Cheese Meatloaf Casserole – Easy to Eat Meal for Busy Family Nights Thumbnail

Mac and Cheese Meatloaf Casserole

Mac and Cheese Meatloaf Casserole is the ultimate comfort food mashup made for busy family nights. This hearty dish layers juicy, savory meatloaf with creamy, cheesy macaroni for a dinner that’s filling, budget-friendly, and crowd-approved. It’s easy to prep, bakes in one dish, and works perfectly for weeknights, potlucks, or make-ahead meals. Whether you’re cooking for a family of three or feeding a hungry crowd, this casserole delivers big flavor with minimal effort. Simple ingredients, cozy vibes, and guaranteed clean plates—this one’s a keeper.
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Prep Time 20 minutes
Cook Time 45 minutes
Course: Dinner, Main Course, Side Dish
Cuisine: American
Ingredients Method Notes

Ingredients
  

  • Ingredients You’ll Need
  • Meatloaf Base
  • 1 pound ground beef
  • ½ cup finely chopped onion
  • ½ cup breadcrumbs
  • 1 large egg
  • ¼ cup milk
  • 1 teaspoon salt
  • ½ teaspoon black pepper
  • Mac & Cheese Layer
  • 2 cups dry elbow macaroni
  • 2 cups shredded cheddar cheese divided
  • Creamy Cheese Sauce
  • 2 tablespoons butter
  • 2 tablespoons all-purpose flour
  • 2 cups milk
  • ½ teaspoon salt
  • ¼ teaspoon black pepper
  • ½ teaspoon paprika
  • ½ teaspoon dry mustard powder

Method
 

Step 1: Heat Things Up

Set your oven to 350°F (175°C) and lightly grease a casserole dish so nothing sticks later.

    Step 2: Build the Meatloaf Layer

    Grab a large bowl and toss in the ground beef, onion, breadcrumbs, egg, milk, salt, and pepper. Mix until everything is evenly blended—don’t overwork it. Press the mixture firmly into the bottom of your prepared baking dish.

      Step 3: First Bake

      Slide the dish into the oven and bake for 20 minutes, just until the meatloaf starts to set.

        Step 4: Cook the Pasta

        While the meatloaf is baking, boil the macaroni according to the package instructions. Drain well and set aside.

          Step 5: Make the Cheese Sauce

          In a saucepan over medium heat, melt the butter. Whisk in the flour and cook for about a minute until smooth. Slowly pour in the milk, whisking constantly, until the sauce thickens. Season with salt, pepper, paprika, and dry mustard. Stir in 1½ cups of the shredded cheese until fully melted and silky.

            Step 6: Layer It Up

            Mix the cooked macaroni into the cheese sauce until coated. Spoon this cheesy pasta mixture evenly over the partially baked meatloaf. Sprinkle the remaining cheese across the top.

              Step 7: Final Bake

              Return the casserole to the oven and bake for another 25 minutes, or until bubbly and golden on top.

                Notes

                Serving Ideas That Make It Even Better

                Add a Fresh Finish
                • Sprinkle chopped parsley for color
                • Top with chives for a mild onion bite
                Balance with Something Light
                • A crisp Caesar salad cuts the richness
                • A simple garden salad adds freshness
                Bread on the Side
                • Garlic bread for cheesy scooping
                • Soft dinner rolls for extra comfort
                Extra Cheese Moment
                • Finish with parmesan or mozzarella for a melty upgrade

                Pro Tips for Best Results

                • Use freshly shredded cheese for smoother melting
                • Cook pasta just to al dente—it finishes in the oven
                • Let the casserole rest 10 minutes before slicing
                • Mix cheeses like Gouda or Monterey Jack for depth
                • Taste and adjust seasoning as needed

                Storage & Reheating

                Refrigerating

                Store leftovers in a sealed container for 3–5 days.

                Freezing

                Divide into portions, wrap well, and freeze for up to 3 months. Label for easy tracking.

                Reheating

                • Oven: Cover with foil and heat at 350°F for 20 minutes
                • Microwave: Heat in 1-minute bursts until hot
                • Stovetop: Warm gently in a skillet, stirring often

                FAQs

                Can I swap the meat?
                 Yes! Ground turkey or lamb work well—just cook thoroughly.
                Want a vegetarian version?
                 Use a plant-based meat substitute and veggie-friendly milk options.
                Can veggies be added?
                 Definitely. Bell peppers, spinach, or even mushrooms blend right in.
                What’s the best way to enjoy leftovers?
                 Reheat and serve with a simple salad for an easy next-day meal.
                How can I customize the cheese sauce?
                 Mix in mozzarella, gouda, or even pepper jack for a flavor twist.

                Final Thoughts

                This Mac and Cheese Meatloaf Casserole delivers pure comfort in every bite. It’s cozy, customizable, and perfect for everything from weeknight dinners to family get-togethers. Once you try it, don’t be surprised if it becomes a repeat request. 💛🍽️